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His
major interests include the characterization of post-translationally
modified proteins and metabolic profiles in humans as response elements upon
exposure to toxicants (pesticides, heavy metals), intervention
protocols with nutritional factors (vitamins, natural
products, functional foods) and as
indicators of chronic disease states(Alzheimer's,
cancer, cardiovascular disease) Essential to these
investigations is the development and validation of
advanced technologies in the proteomics and metabonomic fields primarily involving
the use of hyphenated
techniques based on multi-dimensional chromatography
interfaced with mass
spectrometry.
His research efforts have
resulted in the publication of over 15 scientific
publications and over 25 presentations at scientific
meetings.
He is a member of the
American Society of Mass Spectrometry, the American
Chemical Society,
and the Association of Official Analytical Chemists.
Dr. Spiros D. Garbis completed his PhD (Biochemical and
Molecular Toxicology) and
post-doctoral work at the Department of Medicinal
Chemistry and Pharmacognosy at the
University of Illinois.
His dissertation work involved
the investigation of ADMET
properties (Absorption,
Distribution, Metabolism,
Excretion and Toxicology) of
stable-isotope labeled folates
in humans. Dr. Spiros D.
Garbis has also worked as a
Forensic Chemist for the State of Illinois primarily involved in the analysis of
drug residues and their metabolites in biological
fluids.
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