program         abstracts

Topics

Bringing -omics to the basic science and clinical service

Biomarker Validation

Point-counterpoint session: Quantification in proteomics

 

Confirmed Speakers

Marc Baumann, University of Helsinki

Bruno Domon, ETH Zurich

Vilhem GuryČa, F. Hoffmann-La Roche Ltd.

Jadranka Koehn, Medical University of Vienna

Theo Luider, Erasmus MC

Harald Mischak, Mosaiques-Diagnostics GmbH

Thierry Rabilloud, CEA-Grenoble

Pier Giorgio Righetti, Polytechnic of Milano

George Thireos, IMBB FORTH

Hans Voshol, Novartis Institutes for Biomedical Research

Ioannis Xenarios, Swiss Institute of Bioinformatics 

 

Program                                      

Closing of EuroKUP

HSP meeting: Monday March 30 Tuesday March 31 Wednesday April 1
13.30

Closing of the Urine and Kidney Proteomics (EuroKUP) COST Action meeting (www.eurokup.org)

13.30-17.30 Trip to Mycenae (optional)
17.30-19.00 Registration for the HPS meeting

HPS meeting

 

 

Monday March 30, 2009

 

HPS Opening Lectures

Chairs: A. Vlahou and I. Xenaros

18.30-19.15

T. Rabilloud, CEA-Grenoble

What room for electrophoretic separations in modern proteomics?

19.15-20.00   

P.G. Righetti, Polytechnic of Milano

The ProteoMiner and the FortyNiners: searching for gold nuggets in the proteomic arena

20.00-20.45   

B. Domon, ETH Zurich

Paradigm shift in proteomic biomarker discovery and evaluation

21.00              

Welcome Dinner

 

Tuseday March 31, 2009

 

 

Bringing -omics to the basic science and clinical service

Chairs: P.G Righetti and G. Tsangaris

9.00-9.20

T. Luider,  ErasmusMC

Finding preeclampsoa biomarkers in chorion villus biopsies by mass spectrometry

9.25-9.45

H. Mischak,  Mosaiques-Diagnostics GmbH

CE-MS-based urinary proteomics as a powerful tool in clinical diagnosis, prognosis, and therapy evaluation

9.50-10.10

V. Guryča, F. Hoffmann-La Roche Ltd

Deeper exploration of proteome with a combination of multidimensional peptide separations with accurate mass and time tags (AMT) proteomics approach

10.15-10.35

M. Baumann, University of Helsinki

MS-IMS (Maldi-Imaging) The use of mass spectrometry for tissue imaging

10.40-11.10

Industrial  Workshop:

B. Fathollahi, Caliper Life Sciences

The application of high throughput microchip CE-SDS (LabChip®) in protein sciences

11.10-11.30 Coffee Break    Poster viewing
  Chairs: T. Rabilloud and S. Garbis
11.30-11.50

H. Voshol, Novartis Institutes for Biomedical Research

Pathway analysis using reverse protein arrays

11.55-12.15

I. Xenarios, Swiss Institute of Bioinformatics

Integration of biological knowledge: from avalanche of data to system modelling

12.20-12.40

G. Thireos, IMBB FORTH

Systems biology: Just a slogan or a reality?

12.45-13.15

Industrial Workshop:

M. Macht, Bruker Daltonik GmbH

Pushing the limit in proteomic analyses: a novel mass spectrometer combining ultra-high mass resolution and accuracy for maximum protein sequence coverage

13.15-14.30

Light Lunch    Poster viewing

14.30-15.00

Industrial Workshop: Biorad

A. Sacchi

How to improve a gold standard such as SDS-PAGE or 2D electrophoresis using the new Criterion Stain Free system

 

Scientific Session

Chairs: B. Domon and D. Sanoudou

15.00-15.20

E. Boschetti

Isoelectric pre-fractionation of proteins and peptides with solid-state buffers prior to extensive proteomics analysis

15.20-15.35

M.A. McDowall

An integrated workflow solution for optimized discovery and targeted proteomics research

15.35-15.50

H. Kovarova

Monitoring of anti-cancer therapies and resultant chemoresistance

15.50-16.05

C. Lane

Moving protein candidates through the biomarker research pipeline: from discovery to validation using targeted mass spectrometry workflows

16.05-16.20

S.J. Gadher

Protein profiling of human follicular fluid: quest for biomarkers of ovarian hyperstimulation syndrome

16.20-16.35

M. Scigelova

Advanced techniques for characterizing post-translational modifications on peptides and proteins using electron transfer dissociation

16.35-16.50

S. Garbis

Biomarker discovery in low-grade breast cancer tissue biopsies using a novel quantitative proteomic approach

16.50-17.00

M. Aivaliotis

Urine proteome analysis by two-dimensional gel-based protein separation coupled with nLC-ESI-MS/MS

17.00-17.10

A. Anagnostopoulos

Proteomic analysis of amniotic fluid in pregnancies with Klinefelter syndrome fetuses

17.10-17.30 Coffee Break    Poster viewing
 

Scientific Session: Biomarker Validation

Chairs: H. Voschol and E. Baumann

17.30-17.50

H. Mischak

Mandatory requirements in biomarker identification

17.50-18.10

J. Koehn

FDA-requirements for biomarker validation

18.10-19.30

Point-Counterpoint -Challenging the Expert Session: Peptide/protein Quantification

Righetti (ProteoMiner)

Rabilloud (2DE staining techniques)

Mischak (peptide profiling)

Domon (SRM)

 

  Wednesday April 1, 2009
 

Scientific Session

Chairs: A. Charonis and H. Kovarova

9.00-9.10

T. Economou

ProFI: The new proteomics facility at IMBB

9.10-9.20

E. Balfoussia

Proteomic analysis of superathletes' plasma in a model of severe stress reveal as yet unknown mediator changes

9.20-9.30

E. Fasoli

Searching for allergens in maize cytoplasmic proteins: A proteomic study

9.30-9.40

A. Farinazzo

Mapping the chicken egg white and yolk proteomes with combinatorial peptide ligand libraries

9.40-9.50

J. Zoidakis

Development of a strategy for the analysis of metal-binding proteins in urine

9.50-10.00

D. Glotsos

Proteomic MS-spectra decomposition into intensity-regions for identifying potential biomarkers and improving discrimination accuracy between normal and cancerous spectra

10.00-10.10

E. Giannopoulou

An interactive tool for visualizing jointly properties of proteomic objects

10.10-10.20

P. Tsakanikas

An efficient 2-DE gel image analysis pipeline: Combining contourlets and active contours for reliable spot segmentation and quantification

10.20-10.45 General discussion
10.45-11.30

Educational session

H. Voshol

Tips and Tricks and Reproducibility of 2D PAGE

11.30-12.30 Light Lunch
      End of meeting

 

 

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