|
Marc Baumann,
University of Helsinki |
|
Bruno
Domon, ETH Zurich |
|
Vilhem
GuryČa,
F. Hoffmann-La Roche Ltd. |
|
Jadranka Koehn,
Medical University of Vienna |
|
Theo Luider,
Erasmus MC |
|
Harald Mischak,
Mosaiques-Diagnostics
GmbH |
|
Thierry Rabilloud,
CEA-Grenoble |
|
Pier Giorgio Righetti,
Polytechnic of Milano |
|
George Thireos,
IMBB FORTH |
|
Hans Voshol,
Novartis
Institutes for Biomedical Research |
|
Ioannis Xenarios,
Swiss Institute of Bioinformatics |
|
|
|
13.30 |
Closing of the Urine and Kidney Proteomics (EuroKUP) COST
Action meeting (www.eurokup.org) |
|
13.30-17.30 |
Trip
to Mycenae (optional) |
|
17.30-19.00 |
Registration for the HPS meeting |
|
HPS meeting |
|
|
Monday March
30, 2009
|
|
|
HPS Opening Lectures
Chairs: A. Vlahou and I. Xenaros |
|
18.30-19.15 |
T. Rabilloud,
CEA-Grenoble
What room for electrophoretic separations in modern
proteomics? |
|
19.15-20.00 |
P.G. Righetti,
Polytechnic of Milano
The ProteoMiner and the FortyNiners: searching for gold
nuggets in the proteomic arena |
|
20.00-20.45 |
B. Domon,
ETH Zurich
Paradigm shift in proteomic biomarker discovery and
evaluation |
|
21.00 |
Welcome Dinner |
|
|
Tuseday March 31, 2009
|
|
|
Bringing -omics
to the basic science and clinical service
Chairs: P.G Righetti and G. Tsangaris |
|
9.00-9.20 |
T. Luider,
ErasmusMC
Finding preeclampsoa biomarkers in chorion villus biopsies
by mass spectrometry |
|
9.25-9.45 |
H. Mischak,
Mosaiques-Diagnostics
GmbH
CE-MS-based urinary proteomics as a powerful tool in
clinical diagnosis, prognosis, and therapy evaluation |
|
9.50-10.10 |
V. Guryča,
F. Hoffmann-La Roche Ltd
Deeper
exploration of proteome with a combination of
multidimensional peptide separations with accurate mass and
time tags (AMT) proteomics approach |
|
10.15-10.35 |
M. Baumann,
University of Helsinki
MS-IMS
(Maldi-Imaging) The use of mass spectrometry for tissue
imaging |
|
10.40-11.10 |
Industrial Workshop:
B. Fathollahi, Caliper Life Sciences
The application of high throughput microchip CE-SDS (LabChip®)
in protein sciences |
|
11.10-11.30 |
Coffee Break
Poster viewing |
|
|
Chairs: T. Rabilloud and S. Garbis |
|
11.30-11.50 |
H. Voshol,
Novartis Institutes for Biomedical Research
Pathway analysis using reverse protein arrays |
|
11.55-12.15 |
I.
Xenarios,
Swiss Institute of Bioinformatics
Integration of biological knowledge: from avalanche of data
to system modelling |
|
12.20-12.40 |
G.
Thireos, IMBB FORTH
Systems biology: Just a slogan or a reality? |
|
12.45-13.15 |
Industrial Workshop:
M. Macht, Bruker Daltonik GmbH
Pushing the
limit in proteomic
analyses: a novel mass spectrometer combining ultra-high
mass resolution and accuracy for maximum protein
sequence coverage
|
|
13.15-14.30 |
Light Lunch
Poster viewing
|
|
14.30-15.00 |
Industrial Workshop: Biorad
A. Sacchi
How to
improve a gold standard such as SDS-PAGE or 2D
electrophoresis using the new Criterion Stain Free system |
|
|
Scientific Session
Chairs: B. Domon and D. Sanoudou |
|
15.00-15.20 |
E. Boschetti
Isoelectric
pre-fractionation of proteins and peptides with solid-state
buffers prior to extensive proteomics analysis |
|
15.20-15.35 |
M.A. McDowall
An
integrated workflow solution for optimized discovery and
targeted proteomics research |
|
15.35-15.50 |
H. Kovarova
Monitoring
of anti-cancer therapies and resultant chemoresistance |
|
15.50-16.05 |
C. Lane
Moving
protein candidates through the biomarker research pipeline:
from discovery to validation using targeted mass
spectrometry workflows |
|
16.05-16.20 |
S.J. Gadher
Protein
profiling of human follicular fluid: quest for biomarkers of
ovarian hyperstimulation syndrome |
|
16.20-16.35 |
M. Scigelova
Advanced
techniques for characterizing post-translational
modifications on peptides and proteins using electron
transfer dissociation |
|
16.35-16.50 |
S. Garbis
Biomarker
discovery in low-grade breast cancer tissue biopsies using a
novel quantitative proteomic approach |
|
16.50-17.00 |
M. Aivaliotis
Urine
proteome analysis by two-dimensional gel-based protein
separation coupled with nLC-ESI-MS/MS |
|
17.00-17.10 |
A. Anagnostopoulos
Proteomic
analysis of amniotic fluid in pregnancies with Klinefelter
syndrome fetuses |
|
17.10-17.30 |
Coffee Break
Poster viewing |
|
|
Scientific Session: Biomarker
Validation
Chairs: H. Voschol and
E. Baumann |
|
17.30-17.50 |
H. Mischak
Mandatory
requirements in biomarker identification |
|
17.50-18.10 |
J. Koehn
FDA-requirements
for biomarker validation |
|
18.10-19.30 |
Point-Counterpoint -Challenging the Expert Session:
Peptide/protein Quantification
Righetti
(ProteoMiner)
Rabilloud (2DE staining techniques)
Mischak
(peptide profiling)
Domon (SRM)
|
|
|
Wednesday
April 1, 2009 |
|
|
Scientific Session
Chairs: A. Charonis and H. Kovarova |
|
9.00-9.10 |
T. Economou
ProFI: The
new proteomics facility at IMBB |
|
9.10-9.20 |
E. Balfoussia
Proteomic
analysis of superathletes' plasma in a model of severe
stress reveal as yet unknown mediator changes |
|
9.20-9.30 |
E. Fasoli
Searching
for allergens in maize cytoplasmic proteins: A proteomic
study |
|
9.30-9.40 |
A. Farinazzo
Mapping the chicken egg white and yolk proteomes with combinatorial
peptide ligand libraries |
|
9.40-9.50 |
J. Zoidakis
Development
of a strategy for the analysis of metal-binding proteins in
urine |
|
9.50-10.00 |
D. Glotsos
Proteomic
MS-spectra decomposition into intensity-regions for
identifying potential biomarkers and improving
discrimination accuracy between normal and cancerous spectra |
|
10.00-10.10 |
E. Giannopoulou
An
interactive tool for visualizing jointly properties of
proteomic objects |
|
10.10-10.20 |
P. Tsakanikas
An efficient
2-DE gel image analysis pipeline: Combining contourlets and
active contours for reliable spot segmentation and
quantification |
|
10.20-10.45 |
General
discussion |
|
10.45-11.30 |
Educational session
H. Voshol
Tips and
Tricks and Reproducibility of 2D PAGE |
|
11.30-12.30 |
Light Lunch |
|
|
End of meeting
 |